Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 6/20 | 0.31 |
| ▸ | JAK1 | P23458 | 4/20 | 0.31 |
| ▸ | BRD4 | O60885 | 4/20 | 0.31 |
| ▸ | BRD2 | P25440 | 2/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 3/20 | 0.30 |
| ▸ | FLT3 | P36888 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865157 | 0.91 | DHODH (0.36) | KDM4EMAPTSCN10ABCL6JAK2 | |
| SCHEMBL24865300 | 0.83 | CNR2 (0.34) | KDM4EMAPTBCL6JAK2BRD4 | |
| SCHEMBL24865335 | 0.77 | KIT (0.35) | KDM4EMAPTSCN10ABCL6TRPA1 | |
| SCHEMBL31123228 | 0.74 | BCL6 (0.49) | KDM4EMAPTSCN10ABCL6JAK1 | |
| SCHEMBL24865177 | 0.74 | BCL6 (0.49) | KDM4EMAPTSCN10ABCL6JAK1 | |
| SCHEMBL24865658 | 0.73 | SYK (0.34) | KDM4EMAPTJAK2BRD4 | |
| SCHEMBL24865770 | 0.71 | CNR2 (0.33) | BCL6JAK2 | |
| SCHEMBL24865720 | 0.71 | BCL6 (0.40) | KDM4EMAPTSCN10ABCL6JAK1 | |
| SCHEMBL31123218 | 0.71 | BCL6 (0.40) | KDM4EMAPTSCN10ABCL6JAK1 | |
| SCHEMBL24865334 | 0.70 | GABRG2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |