Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31123218 | 1.00 | BCL6 (0.40) | BCL6JAK1JAK3GPR55GABRG2 | |
| SCHEMBL24865177 | 0.85 | BCL6 (0.49) | BCL6JAK1JAK3MAPTKDM4E | |
| SCHEMBL31123228 | 0.85 | BCL6 (0.49) | BCL6JAK1JAK3MAPTKDM4E | |
| SCHEMBL24865740 | 0.83 | BCL6 (0.40) | BCL6JAK1JAK3GABRG2GABRB3 | |
| SCHEMBL31123207 | 0.77 | GABRG2 (0.45) | GABRG2GABRB3GABRA5 | |
| SCHEMBL24865334 | 0.77 | GABRG2 (0.45) | GABRG2GABRB3GABRA5 | |
| SCHEMBL30336132 | 0.76 | BCL6 (0.49) | BCL6JAK1JAK3MAPTKDM4E | |
| SCHEMBL24865152 | 0.76 | BCL6 (0.49) | BCL6JAK1JAK3MAPTKDM4E | |
| SCHEMBL24865639 | 0.75 | GABRG2 (0.43) | BCL6GABRG2GABRB3GABRA5MAPT | |
| SCHEMBL24865430 | 0.74 | KIF11 (0.49) | JAK1JAK3GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |