Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865300 | 0.87 | CNR2 (0.34) | CNR2JAK2BCL6HRH3 | |
| SCHEMBL24865658 | 0.76 | SYK (0.34) | CNR2JAK2HRH3 | |
| SCHEMBL24865741 | 0.76 | CNR2 (0.34) | CNR2JAK2EGFRBCL6HRH3 | |
| SCHEMBL24865771 | 0.76 | MAPK13 (0.33) | CNR2EGFRBCL6 | |
| SCHEMBL24865745 | 0.73 | MAPK10 (0.44) | EGFR | |
| SCHEMBL24865618 | 0.72 | CNR2 (0.36) | CNR2JAK2BCL6HRH3 | |
| SCHEMBL30885112 | 0.72 | CNR2 (0.36) | CNR2JAK2BCL6HRH3 | |
| SCHEMBL25189837 | 0.71 | CNR2 (0.34) | CNR2JAK2EGFRBCL6 | |
| SCHEMBL24865675 | 0.71 | OPRK1 (0.36) | CNR2HRH3 | |
| SCHEMBL31123214 | 0.70 | BCL6 (0.49) | CNR2JAK2BCL6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |