Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865637 | 0.94 | ALDH1A1 (0.33) | ALDH1A1HPGDMAPTMAPK1GAA | |
| SCHEMBL24865660 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HPGDMAPTMAPK1HTT | |
| SCHEMBL24865658 | 0.74 | SYK (0.34) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL30336449 | 0.74 | BCL6 (0.38) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL24865227 | 0.74 | BCL6 (0.38) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL24865300 | 0.71 | CNR2 (0.34) | MAPTKDM4E | |
| SCHEMBL24865643 | 0.68 | PDGFRB (0.37) | ALDH1A1MAPTMAPK1GAAKDM4E | |
| SCHEMBL24865635 | 0.67 | BCL6 (0.39) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL31123320 | 0.67 | BCL6 (0.39) | ALDH1A1MAPTMAPK1GAASMN1; SMN2 | |
| SCHEMBL24865708 | 0.65 | MEN1 (0.33) | ALDH1A1HPGDMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |