Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865467 | 0.82 | ALDH1A1 (0.33) | ALDH1A1HTTMAPTHPGDMEN1 | |
| SCHEMBL24865637 | 0.82 | ALDH1A1 (0.33) | ALDH1A1HTTMAPTHPGDMEN1 | |
| SCHEMBL24865225 | 0.73 | MAPT (0.44) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL30336545 | 0.73 | MAPT (0.44) | ALDH1A1HTTMAPTLMNA | |
| SCHEMBL24865658 | 0.72 | SYK (0.34) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL24865300 | 0.69 | CNR2 (0.34) | MAPT | |
| SCHEMBL24865643 | 0.65 | PDGFRB (0.37) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL24865708 | 0.64 | MEN1 (0.33) | ALDH1A1MAPTLMNATDP1HPGD | |
| SCHEMBL31053539 | 0.64 | EPHX2 (0.39) | MAPTLMNAHPGDKMT2A | |
| SCHEMBL14217256 | 0.64 | ALDH1A1 (0.57) | ALDH1A1HTTMAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |