Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865708 | 0.75 | MEN1 (0.33) | PKMMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL24865601 | 0.73 | MEN1 (0.31) | PKMMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL24865739 | 0.72 | ENPP2 (0.40) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL24865688 | 0.72 | EGFR (0.47) | PKMEGFRMEN1TP53MAPT | |
| SCHEMBL31035921 | 0.71 | PRKCI (0.55) | PKMEGFRGRM4HTR2BMEN1 | |
| SCHEMBL9400551 | 0.71 | PRKCI (0.55) | PKMEGFRGRM4HTR2BMEN1 | |
| SCHEMBL24865752 | 0.71 | PTK2 (0.38) | EGFRMEN1MAPTKMT2ALMNA | |
| SCHEMBL24865658 | 0.69 | SYK (0.34) | MEN1TP53MAPTKMT2AKDM4E | |
| SCHEMBL24865643 | 0.68 | PDGFRB (0.37) | MEN1MAPTKMT2AKDM4ETDP1 | |
| SCHEMBL15152207 | 0.68 | MAOB (0.63) | PKMEGFRGRM4HTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |