Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.38 |
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | GAK | O14976 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.36 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.36 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865708 | 0.79 | MEN1 (0.33) | MEN1KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL24865601 | 0.74 | MEN1 (0.31) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL24865688 | 0.73 | EGFR (0.47) | MEN1KMT2AEGFRMAPK1ALDH1A1 | |
| SCHEMBL24865612 | 0.71 | PKM (0.38) | MEN1KMT2AEGFRMAPK1LMNA | |
| SCHEMBL24865739 | 0.69 | ENPP2 (0.40) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL24865658 | 0.68 | SYK (0.34) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL24865643 | 0.68 | PDGFRB (0.37) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL17948239 | 0.65 | MEN1 (0.71) | BRAFMEN1KMT2AGAKEGFR | |
| SCHEMBL24865623 | 0.64 | KDM1A (0.39) | BRAFMEN1KMT2AEGFRMAPK1 | |
| SCHEMBL3631829 | 0.64 | BRAF (0.70) | BRAFMEN1KMT2AGAKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |