Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865708 | 0.78 | MEN1 (0.33) | ALDH1A1ALOX15MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3030672 | 0.74 | KDM1A (0.59) | KDM1AALDH1A1ALOX15GAAJAK2 | |
| SCHEMBL24865727 | 0.73 | MAPK1 (0.30) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL28557487 | 0.69 | KDM1A (0.63) | KDM1AALDH1A1ALOX15GAAMAPT | |
| SCHEMBL1268756 | 0.69 | ALDH1A1 (0.50) | KDM1AALDH1A1ALOX15GAAMAPT | |
| SCHEMBL31726567 | 0.69 | ALDH1A1 (0.50) | KDM1AALDH1A1ALOX15GAAMAPT | |
| SCHEMBL9877100 | 0.68 | ALDH1A1 (0.39) | KDM1AALDH1A1ALOX15GAAMAPT | |
| Hydrochloric Acid SCHEMBL11291701 | 0.68 | ALDH1A1 (0.48) | KDM1AALDH1A1ALOX15GAAMAPT | |
| SCHEMBL24865688 | 0.68 | EGFR (0.47) | KDM1AALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL9649012 | 0.67 | ALDH1A1 (0.53) | KDM1AALDH1A1ALOX15GAAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |