Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865623 | 0.73 | KDM1A (0.39) | MAPK1SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL292857 | 0.72 | RAB9A (0.47) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL24865688 | 0.70 | EGFR (0.47) | MAPK1SMN1; SMN2NPC1RAB9AATM | |
| SCHEMBL24865791 | 0.69 | HRH3 (0.35) | SMN1; SMN2 | |
| SCHEMBL25888283 | 0.67 | NPC1 (0.43) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL25007291 | 0.67 | KIF11 (0.47) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL24865601 | 0.66 | MEN1 (0.31) | LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL9473731 | 0.66 | ALDH1A1 (0.52) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL23894646 | 0.66 | MAPT (0.44) | MAPK1SMN1; SMN2NPC1LMNACASP3 | |
| SCHEMBL24865708 | 0.65 | MEN1 (0.33) | MAPK1SMN1; SMN2LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |