Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865699 | 0.90 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL24865648 | 0.86 | GRM4 (0.40) | ALDH1A1GRM4MAPTGAAMEN1 | |
| SCHEMBL24865010 | 0.82 | MAPT (0.46) | GRM4MAPTRAB9ANSD2NOTUM | |
| SCHEMBL24865084 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL24865640 | 0.77 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL24865211 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL24865638 | 0.75 | SMN1; SMN2 (0.43) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL24865209 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1LMNASMN1; SMN2MAPTGAA | |
| SCHEMBL24865664 | 0.75 | EGFR (0.53) | ALDH1A1LMNAGRM4SMN1; SMN2MAPT | |
| SCHEMBL25193365 | 0.72 | RAB9A (0.58) | ALDH1A1LMNASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999259-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |