Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28841590 | 0.82 | — | — | |
| Piperazine SCHEMBL238 | 0.78 | — | — | |
| SCHEMBL2373879 | 0.78 | HIF1A (1.00) | — | |
| Piperazine SCHEMBL8010246 | 0.78 | — | — | |
| SCHEMBL576335 | 0.78 | HIF1A (1.00) | — | |
| SCHEMBL22003 | 0.78 | HIF1A (1.00) | — | |
| Piperazine SCHEMBL734764 | 0.78 | HIF1A (1.00) | — | |
| SCHEMBL5033222 | 0.78 | HIF1A (1.00) | — | |
| SCHEMBL3999265 | 0.78 | HIF1A (1.00) | — | |
| SCHEMBL7052601 | 0.78 | HIF1A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315839-A1 | PEST CONTROL COMPOSITION INCLUDING NOVEL IMINOPYRIDINE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-10-23 | — | — | US | claimed |
| WO-2013129688-A1 | PEST CONTROL COMPOSITION INCLUDING NOVEL IMINOPYRIDINE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2013-09-06 | — | — | WO | claimed |
| EP-2633756-A1 | Pest control composition including novel iminopyridine derivate | Meiji Seika Pharma Co., Ltd. (JP) | 2013-09-04 | — | — | EP | claimed |
| CN-102325451-A | Composition to control harmful organisms that contains 16-keto aspergillimide | MEIJI SEIKA KAISHA | 2012-01-18 | — | — | CN | claimed |
| US-20110263520-A1 | COMPOSITION FOR USE IN CONTROLLING HARMFUL ORGANISMS THAT CONTAINS 16-KETO ASPERGILLIMIDE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2011-10-27 | — | — | US | claimed |
| EP-2380439-A1 | COMPOSITION TO CONTROL HARMFUL ORGANISMS THAT CONTAINS 16-KETO ASPERGILLIMIDE | Meiji Seika Pharma Co., Ltd. (JP) | 2011-10-26 | — | — | EP | claimed |
| US-11771086-B2 | Pest control composition including novel iminopyridine derivative | MMAG CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| CN-112244015-B | Pest control composition comprising novel iminopyridine derivatives | 株式会社MMAG | 2022-05-17 | — | — | CN | disclosed |
| CN-111771885-B | Pest control composition comprising novel iminopyridine derivatives | 株式会社MMAG | 2022-05-17 | — | — | CN | disclosed |
| CN-112244015-A | Pest control composition comprising novel iminopyridine derivatives | 明治制果药业株式会社 | 2021-01-22 | — | — | CN | disclosed |
| CN-108684667-B | Pest control composition comprising novel iminopyridine derivatives | 明治制果药业株式会社 | 2020-12-01 | — | — | CN | disclosed |
| CN-111771885-A | Pest control composition comprising novel iminopyridine derivatives | 明治制果药业株式会社 | 2020-10-16 | — | — | CN | disclosed |
| US-20200315172-A1 | PEST CONTROL COMPOSITION INCLUDING NOVEL IMINOPYRIDINE DERIVATIVE | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2020-10-08 | — | — | US | disclosed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| CN-85109721-A | Preparation has the ectoparasite of the no disease homoiothermic animal of control and the method for endoparasite compositions | — | 1987-07-15 | — | — | CN | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |