⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24874279 | 0.81 | — | — | |
| SCHEMBL24874239 | 0.81 | GABRA1 (0.39) | — | |
| SCHEMBL24248985 | 0.72 | LMNA (0.40) | — | |
| SCHEMBL25883867 | 0.70 | — | — | |
| SCHEMBL16744230 | 0.67 | NPC1 (0.40) | — | |
| SCHEMBL22793068 | 0.62 | ALDH1A1 (0.36) | — | |
| SCHEMBL2945627 | 0.62 | NPC1 (0.41) | — | |
| SCHEMBL22792586 | 0.61 | ALDH1A1 (0.36) | — | |
| SCHEMBL21678005 | 0.61 | TRPV1 (0.51) | — | |
| SCHEMBL24253547 | 0.61 | ALOX15 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230069804-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| US-20230020922-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-19 | — | — | US | disclosed |
| US-20230008867-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |