Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 10/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131399 | 0.76 | CA2 (0.40) | CA2EGLN2NPC1RAB9AALDH1A1 | |
| SCHEMBL22363326 | 0.74 | GAA (0.41) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL31275373 | 0.73 | LOXL2 (0.40) | CFTRMEN1KMT2A | |
| SCHEMBL24869252 | 0.71 | PPARD (0.38) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13388610 | 0.70 | CFTR (0.39) | CFTREGLN1EGLN2VEGFAFLT1 | |
| SCHEMBL23580680 | 0.69 | CFTR (0.46) | CFTREGLN1EGLN2VEGFAFLT1 | |
| SCHEMBL30131356 | 0.68 | EGLN2 (0.41) | EGLN2NPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL1105993 | 0.67 | MEN1 (0.43) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL24661703 | 0.67 | ATM (0.47) | NPC1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL19975802 | 0.66 | ALDH1A1 (0.47) | RAB9AALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |