Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30131356 | 0.92 | EGLN2 (0.41) | EGLN2FTONR3C1CYP1A2CYP3A4 | |
| SCHEMBL30131474 | 0.86 | LOXL2 (0.45) | EGLN2FTONR3C1CYP1A2CYP3A4 | |
| SCHEMBL30131499 | 0.80 | EGLN2 (0.43) | EGLN2FTOCTSAALDH1A1POLB | |
| SCHEMBL30875096 | 0.78 | RAB9A (0.46) | EGLN2FTOALDH1A1HSD17B13HPGD | |
| SCHEMBL24869259 | 0.76 | CFTR (0.41) | CA2EGLN2ALDH1A1NPC1RAB9A | |
| SCHEMBL30875055 | 0.76 | EGLN2 (0.44) | EGLN2FTOCTSAALDH1A1POLB | |
| SCHEMBL30131408 | 0.75 | NPC1 (0.47) | EGLN2FTOALDH1A1POLBHPGD | |
| SCHEMBL30875025 | 0.74 | ALDH1A1 (0.43) | EGLN2FTOCTSAALDH1A1POLB | |
| SCHEMBL29459608 | 0.74 | POLB (0.47) | EGLN2FTOPOLBHPGDNPC1 | |
| SCHEMBL31384297 | 0.73 | P2RX7 (0.52) | EGLN2FTOCTSAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | claimed |
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |