Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84400 | 0.75 | PGK1 (0.38) | KDM4EHPGDLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL799306 | 0.69 | PIK3CA (0.38) | ALDH1A1 | |
| SCHEMBL6124792 | 0.66 | HDAC4 (0.42) | KDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL8737264 | 0.66 | HDAC4 (0.38) | HPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10141662 | 0.65 | TRPM8 (0.39) | MAPTHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10141676 | 0.65 | ALDH1A1 (0.38) | HPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10085321 | 0.65 | CHRNB2 (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10080963 | 0.65 | P2RX3 (0.43) | — | |
| SCHEMBL10080967 | 0.64 | HTR2A (0.37) | KDM4EMAPTLMNAALDH1A1GAA | |
| SCHEMBL21303908 | 0.63 | MAPT (0.40) | KDM4EMAPTHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |