Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487218 | 0.82 | — | — | |
| SCHEMBL12332806 | 0.81 | POLB (0.35) | POLBGRK2CTDSP1PTGS2 | |
| SCHEMBL2489020 | 0.72 | KDM1A (0.36) | — | |
| SCHEMBL14752786 | 0.62 | ALDH1A1 (0.37) | POLB | |
| SCHEMBL2481113 | 0.62 | ALDH1A1 (0.36) | — | |
| SCHEMBL14739957 | 0.61 | KDM1A (0.31) | — | |
| SCHEMBL22952727 | 0.61 | ADORA2B (0.30) | — | |
| SCHEMBL11611099 | 0.61 | PTGS2 (0.36) | POLBGRK2CTDSP1PTGS2 | |
| SCHEMBL14739625 | 0.59 | KDM1A (0.34) | — | |
| SCHEMBL2483252 | 0.59 | KDM1A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376402-B2 | 1, 2, 4-triazole derivatives and their anti-microbial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-28 | — | — | US | disclosed |
| CN-102858755-B | 1,2,4-triazole derivative and anti-mycobacterium activity thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-25 | — | — | CN | disclosed |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | COUNCIL SCIENT IND RES (IN) | 2015-03-12 | — | — | US | disclosed |
| US-8865910-B2 | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-21 | — | — | US | disclosed |
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-03-07 | — | — | US | disclosed |
| CN-102858755-A | 1, 2, 4-triazole derivatives and their anti mycobacterial activity | COUNCIL SCIENT IND RES | 2013-01-02 | — | — | CN | disclosed |
| WO-2011111077-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060045-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI MYCOBACTERIAL ACTIVITY | NAT1, CBR3, NOX3 | POLB 415/4885GRK2 2541/4885CTDSP1 1007/4885 |
| US-20150073026-A1 | 1, 2, 4-TRIAZOLE DERIVATIVES AND THEIR ANTI-MICROBIAL ACTIVITY | CYP51A1, TALDO1, IL33 | POLB 113/4885GRK2 2619/4885CTDSP1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.