Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1517630 | 0.82 | NR2F2 (0.35) | NMT1MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL919364 | 0.79 | MAPT (0.38) | MAPK8NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL469635 | 0.78 | KDM4E (0.39) | CDK8ACVR1KDM4ELMNAPOLB | |
| SCHEMBL3789703 | 0.77 | MAPK8 (0.38) | MAPK8NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL919414 | 0.76 | KMT2A (0.37) | MAPK8KMT2AMEN1MAPK9LMNA | |
| SCHEMBL466412 | 0.74 | MAPT (0.36) | CDK8ACVR1LMNASMN1; SMN2NR3C1 | |
| SCHEMBL22031802 | 0.74 | KMT2A (0.36) | NMT1MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL29457662 | 0.74 | KMT2A (0.36) | NMT1MAPK8KMT2AMEN1MAPK9 | |
| SCHEMBL510530 | 0.73 | MAPK8 (0.36) | MAPK8KMT2AMAPK9CDK8ACVR1 | |
| SCHEMBL513860 | 0.71 | MAPK8 (0.42) | NMT1MAPK8KMT2AMEN1CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379509-B1 | HERBICIDAL AND INSECTICIDAL PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER IP GMBH (DE) | 2016-02-17 | — | — | EP | disclosed |
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| EP-2379509-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | Bayer CropScience AG (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| WO-2010078912-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2010-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | NMT1 2095/4885MAPK8 3302/4885NPC1 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.