Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789703 | 0.92 | MAPK8 (0.38) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1517630 | 0.86 | NR2F2 (0.35) | MAPTALDH1A1KMT2AMEN1MAPK8 | |
| SCHEMBL919414 | 0.85 | KMT2A (0.37) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL469635 | 0.81 | KDM4E (0.39) | MAPTALDH1A1HPGDLMNACDK8 | |
| SCHEMBL510530 | 0.79 | MAPK8 (0.36) | MAPTSMN1; SMN2KMT2AMAPK8MAPK9 | |
| SCHEMBL2487475 | 0.79 | NMT1 (0.39) | MAPTSMN1; SMN2KMT2AMEN1MAPK8 | |
| SCHEMBL919279 | 0.75 | MAPT (0.33) | MAPTSMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL16642353 | 0.74 | CRHR1 (0.38) | MAPTALDH1A1HPGDLMNACDK8 | |
| SCHEMBL22031802 | 0.74 | KMT2A (0.36) | MAPTSMN1; SMN2KMT2AMEN1HPGD | |
| SCHEMBL29457662 | 0.74 | KMT2A (0.36) | MAPTSMN1; SMN2KMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003692-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| WO-2010069526-A1 | HERBICIDALLY AND INSECTICIDALLY EFFECTIVE PHENYL-SUBSTITUED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003692-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | MAPT 4507/4885ALDH1A1 1015/4885SMN1; SMN2 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.