Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31679842 | 0.79 | LMNA (0.63) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL24876379 | 0.78 | LMNA (0.63) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL31679936 | 0.78 | LMNA (0.63) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL31679964 | 0.74 | LMNA (0.60) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL24876074 | 0.74 | LMNA (0.60) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL31679833 | 0.72 | LMNA (0.50) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL24876599 | 0.72 | LMNA (0.48) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL31679983 | 0.72 | LMNA (0.48) | POLBMAPTMEN1KMT2ASMPD1 | |
| SCHEMBL24876238 | 0.67 | PKM (0.34) | MEN1KMT2APKMGRIN2DGRIN3B | |
| SCHEMBL24876607 | 0.66 | GRIN2D (0.31) | MEN1KMT2AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |