Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 9/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22337340 | 0.69 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL20903973 | 0.68 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL24015503 | 0.68 | KDM4E (0.41) | RIPK1KDM4E | |
| SCHEMBL31696458 | 0.67 | GAA (0.39) | EPHX2KMT2A | |
| SCHEMBL24015506 | 0.66 | AKT1 (0.36) | SMPD3KDM4EADORA2AADORA1 | |
| SCHEMBL19043880 | 0.66 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL22337341 | 0.64 | CHRNB2 (0.32) | — | |
| SCHEMBL13653085 | 0.63 | PTGS2 (0.61) | ALDH1A1LMNA | |
| SCHEMBL19659265 | 0.63 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL18403238 | 0.62 | SMN1; SMN2 (0.37) | EPHX2KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |