Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778271 | 0.84 | KDM4E (0.52) | KDM4EPOLBGAAHPGDATM | |
| SCHEMBL1134962 | 0.82 | DRD2 (0.54) | KDM4EPOLBGAAFOLH1HPGD | |
| SCHEMBL1135013 | 0.81 | LMNA (0.52) | KDM4EPOLBGAAFOLH1ATM | |
| SCHEMBL9511746 | 0.78 | HPGD (0.68) | KDM4EPOLBHPGDNPC1RAB9A | |
| SCHEMBL16725467 | 0.77 | FOLH1 (0.49) | KDM4EPOLBGAAFOLH1HPGD | |
| SCHEMBL24883478 | 0.77 | FOLH1 (0.61) | KDM4EPOLBGAAFOLH1HPGD | |
| SCHEMBL23260943 | 0.76 | NPC1 (0.65) | KDM4EPOLBHPGDFYNNPC1 | |
| SCHEMBL5555283 | 0.76 | RAB9A (0.64) | KDM4EHPGDNPC1RAB9AL3MBTL1 | |
| SCHEMBL13778268 | 0.75 | SMN1; SMN2 (0.51) | KDM4EPOLBGAAHPGDATM | |
| SCHEMBL10020214 | 0.75 | HPGD (0.79) | KDM4EPOLBHPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283523-A1 | 2,3-DIHYDROBENZO[B][L,4]DIOXIN-6-YL CONTAINING COMPOUNDS USEFUL AS IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-12 | — | — | WO | disclosed |