Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27671651 | 0.91 | CYP3A4 (0.49) | PIN1CYP3A4CYP2D6KCNN4LMNA | |
| SCHEMBL10334725 | 0.87 | NPSR1 (0.45) | PIN1CYP3A4CYP2D6ALDH1A1NPSR1 | |
| SCHEMBL2488944 | 0.86 | LMNA (0.50) | CYP3A4CYP2D6KCNN4LMNAALDH1A1 | |
| SCHEMBL27585378 | 0.86 | CYP3A4 (0.63) | PIN1CYP3A4CYP2D6KCNN4LMNA | |
| SCHEMBL10334703 | 0.83 | CYP3A4 (0.54) | CYP3A4CYP2D6LMNAALDH1A1NPSR1 | |
| SCHEMBL11426878 | 0.83 | ABCB11 (0.54) | CYP3A4ALDH1A1NPSR1POLBTSHR | |
| SCHEMBL11429355 | 0.83 | ALDH1A1 (0.47) | PIN1CYP3A4LMNAALDH1A1RECQL | |
| SCHEMBL9292333 | 0.83 | ALDH1A1 (0.53) | KCNN4LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27916287 | 0.82 | CES1 (0.56) | PIN1KCNN4ALDH1A1RECQLMMP8 | |
| SCHEMBL10334692 | 0.81 | KCNN4 (0.47) | CYP3A4CYP2D6KCNN4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| EP-1855529-B1 | SPIROKETAL-SUBSTITUTED CYCLIC KETOENOLS | BAYER CROPSCIENCE AG (DE) | 2013-12-18 | — | — | EP | claimed |
| EP-1966135-B1 | 3'-ALKOXY-SPIROCYCLOPENTYL-SUBSTITUTED TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2013-10-09 | — | — | EP | claimed |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | claimed |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | BAYER CROPSCIENCE AG (DE) | 2007-04-26 | — | — | US | claimed |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | claimed |
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-01-18 | — | — | US | claimed |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | claimed |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| US-20060160703-A1 | Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | BAYER CROPSCIENCE AG (DE) | 2005-03-10 | — | — | US | claimed |
| US-20050009705-A1 | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | US | claimed |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | BAYER CROPSCIENCE K.K. (JP) | 2004-07-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015664-A1 | 2,4,6-Phenyl substituted cyclic ketoenols | CYP4X1, KDM4E, KCNE1 | PIN1 459/4885CYP3A4 58/4885CYP2D6 60/4885 |
| US-20070066488-A1 | Hetaryl-substituted pyrazolidindione derivatives with pesticidal characteristics | DDT, CYP1A2, HPD | PIN1 181/4885CYP3A4 8/4885CYP2D6 11/4885 |
| US-20070093391-A1 | 4-Biphenyl-substituted pyrazolidin-3 5-diones pesticide agent and/or microbicide and/or herbicide | DDT, CYP4X1, HPD | PIN1 403/4885CYP3A4 21/4885CYP2D6 32/4885 |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | WEE1, KCNE1, CCNE1 | PIN1 104/4885CYP3A4 69/4885CYP2D6 130/4885 |
| US-20070129252-A1 | 2-Halo-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | TBCA, CA6, TRIP13 | PIN1 155/4885CYP3A4 576/4885CYP2D6 25/4885 |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | CYP2W1, CYP4Z1, CYP2E1 | PIN1 76/4885CYP3A4 54/4885CYP2D6 19/4885 |
| US-20050009705-A1 | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners | TARS2, TST, DDT | PIN1 89/4885CYP3A4 173/4885CYP2D6 31/4885 |
| US-20060160703-A1 | Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners | DDT, DDX41, DDC | PIN1 635/4885CYP3A4 157/4885CYP2D6 12/4885 |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | DDT, LAGE3, KYAT1 | PIN1 173/4885CYP3A4 144/4885CYP2D6 10/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | PIN1 1126/4885CYP3A4 28/4885CYP2D6 29/4885 |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | DDT, DDC, DAO | PIN1 249/4885CYP3A4 152/4885CYP2D6 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.