Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 7/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 7/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24890844 | 0.90 | PDK1 (0.52) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL18392314 | 0.87 | RAB9A (0.63) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL24890947 | 0.81 | DGAT1 (0.47) | DGAT1KDM5AKDM4CKDM5BMRGPRX4 | |
| SCHEMBL8446706 | 0.81 | NPC1 (0.72) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL4579112 | 0.78 | NPC1 (0.49) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL13349382 | 0.76 | ALDH1A1 (0.64) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL18392313 | 0.75 | PDK1 (0.50) | PDK1PDK2PDK3PDK4KDM4E | |
| SCHEMBL8276286 | 0.73 | L3MBTL1 (0.57) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL6092832 | 0.73 | PDK1 (0.46) | PDK1PDK2PDK3PDK4NPC1 | |
| SCHEMBL16595915 | 0.73 | NPC1 (0.57) | PDK1PDK2PDK3PDK4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |