Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 8/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892005 | 0.75 | FPR2 (0.49) | FPR2 | |
| SCHEMBL24891651 | 0.72 | MAOA (0.49) | FPR2FPR1KMT2AP2RX7HDAC1 | |
| SCHEMBL7824367 | 0.67 | RAB9A (0.72) | KMT2ARAB9AMEN1 | |
| SCHEMBL24892105 | 0.67 | MAOA (0.46) | FPR2FPR1KMT2AP2RX7HDAC1 | |
| SCHEMBL24891682 | 0.67 | MAOA (0.49) | KMT2ANPC1RAB9AP2RX7HDAC1 | |
| SCHEMBL30074435 | 0.66 | KMT2A (0.53) | FPR2KMT2ANPC1RAB9AHDAC1 | |
| SCHEMBL21025340 | 0.65 | FPR2 (0.59) | FPR2FPR1 | |
| SCHEMBL22453144 | 0.65 | MAOA (0.50) | FPR2FPR1KMT2AHDAC1MEN1 | |
| SCHEMBL19473737 | 0.64 | RAB9A (0.64) | FPR2FPR1KMT2ANPC1RAB9A | |
| SCHEMBL23509616 | 0.64 | RAB9A (0.64) | FPR2FPR1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |