Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 5/20 | 0.34 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30180918 | 0.84 | TMPRSS2 (0.40) | TMPRSS2NAMPT | |
| SCHEMBL30180922 | 0.84 | WNT3A (0.34) | WNT3ATP53MAPTNAMPT | |
| SCHEMBL30180862 | 0.84 | WNT3A (0.33) | WNT3ACDK13CDK12TMPRSS2TP53 | |
| SCHEMBL24891674 | 0.84 | WNT3A (0.34) | WNT3ATP53MAPTNAMPT | |
| SCHEMBL24891721 | 0.79 | NAMPT (0.31) | WNT3ATP53MAPTNAMPT | |
| SCHEMBL24892079 | 0.78 | WNT3A (0.39) | WNT3ACDK13CDK12TMPRSS2NAMPT | |
| SCHEMBL30180901 | 0.73 | WNT3A (0.38) | WNT3ACDK13CDK12TP53MAPT | |
| SCHEMBL24891824 | 0.73 | WNT3A (0.38) | WNT3ACDK13CDK12TP53MAPT | |
| SCHEMBL24671002 | 0.72 | F2 (0.38) | WNT3ATMPRSS2TP53MAPTNAMPT | |
| SCHEMBL30180909 | 0.72 | TMPRSS2 (0.39) | WNT3ATMPRSS2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |