Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671549 | 0.82 | TP53 (0.40) | F2ROCK2TMPRSS2TP53MAPT | |
| SCHEMBL24669239 | 0.81 | MMP12 (0.38) | TMPRSS2TP53MAPTNAMPTNPC1 | |
| SCHEMBL24891885 | 0.80 | TMPRSS2 (0.45) | F2TMPRSS2MAPTNAMPTNPC1 | |
| SCHEMBL24669387 | 0.80 | TMPRSS2 (0.45) | F2TMPRSS2MAPTNAMPTNPC1 | |
| SCHEMBL24671535 | 0.80 | TMPRSS2 (0.39) | F2TMPRSS2TP53MAPTNAMPT | |
| SCHEMBL29802997 | 0.79 | PTPN11 (0.39) | F2ROCK2TMPRSS2TP53MAPT | |
| SCHEMBL30180918 | 0.79 | TMPRSS2 (0.40) | F2TMPRSS2NAMPTNPC1RAB9A | |
| SCHEMBL24669641 | 0.79 | EGLN1 (0.41) | F2MAPTNAMPTNPC1ALDH1A1 | |
| SCHEMBL24670971 | 0.79 | WNT3A (0.47) | MAPTWNT3ANAMPT | |
| SCHEMBL24671486 | 0.79 | MAPT (0.38) | F2TMPRSS2TP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |