Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30182966 | 0.83 | SMN1; SMN2 (0.40) | HTTGLAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24891984 | 0.77 | KDM4E (0.38) | HTTGLAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24891788 | 0.75 | HTT (0.46) | HTTGLAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24892268 | 0.69 | ALDH1A1 (0.72) | HTTGLAKDM4EALDH1A1HPGD | |
| SCHEMBL24892008 | 0.68 | ALDH1A1 (0.55) | HTTGLAKDM4EALDH1A1HPGD | |
| SCHEMBL24891797 | 0.66 | ALDH1A1 (0.69) | HTTGLAKDM4EALDH1A1HPGD | |
| SCHEMBL28308550 | 0.65 | NSD2 (0.44) | HTTGLAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16935306 | 0.61 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDGAAKMT2A | |
| SCHEMBL24590223 | 0.60 | HTT (0.39) | HTTGLAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24256904 | 0.60 | L3MBTL1 (0.83) | HTTGLAKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285583-A1 | 5,6,7,8-TETRAHYDRO-2,6- AND 2,7-NAPHTHYRIDINE DERIVATIVES FOR USE IN THE TREATMENT OF DISEASES RESPONSIVE TO CITRATE TRANSPORTER MODULATION | ETERNYGEN UK LTD. (GB) | 2023-01-19 | — | — | WO | disclosed |