Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24893376 | 0.90 | HTT (0.55) | RAB9AMEN1KMT2APOLBHTT | |
| SCHEMBL24893374 | 0.90 | MEN1 (0.43) | RAB9AACACBMEN1KMT2ATERT | |
| SCHEMBL24893398 | 0.90 | TERT (0.46) | RAB9AACACBMEN1KMT2ATERT | |
| SCHEMBL24893399 | 0.89 | NPC1 (0.43) | RAB9AMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL24893377 | 0.88 | HTT (0.42) | MEN1KMT2AHTTMAPTALDH1A1 | |
| SCHEMBL24893375 | 0.87 | KDM4E (0.44) | MEN1KMT2ATERTPOLBHTT | |
| SCHEMBL24893409 | 0.87 | ACACB (0.50) | ACACBPOLBALBHTTALDH1A1 | |
| SCHEMBL24893407 | 0.86 | MMP13 (0.46) | RAB9AHTTSMN1; SMN2 | |
| SCHEMBL24901281 | 0.85 | ACACB (0.48) | RAB9AACACBMEN1KMT2ATERT | |
| SCHEMBL24893373 | 0.85 | TERT (0.46) | RAB9AACACBMEN1KMT2ATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285371-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2023-01-19 | — | — | WO | disclosed |
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |