Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24893490 | 0.87 | MMP13 (0.49) | MMP13MMP2MMP8MMP9 | |
| SCHEMBL24893418 | 0.86 | RAB9A (0.47) | HTTRAB9ASMN1; SMN2 | |
| SCHEMBL24893409 | 0.82 | ACACB (0.50) | HTT | |
| SCHEMBL24893406 | 0.79 | ADK (0.46) | — | |
| SCHEMBL24893376 | 0.79 | HTT (0.55) | NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4606051 | 0.79 | HNF4A (0.54) | NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL24893400 | 0.79 | SHMT2 (0.39) | RAB9ASMN1; SMN2 | |
| SCHEMBL26098043 | 0.78 | MMP2 (0.50) | MMP13MMP2MMP8HTTMMP9 | |
| SCHEMBL24893399 | 0.78 | NPC1 (0.43) | NPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL24893377 | 0.77 | HTT (0.42) | HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285371-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2023-01-19 | — | — | WO | disclosed |
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |