Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | FASN | P49327 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24893406 | 0.89 | ADK (0.46) | FASNL3MBTL1SHMT2 | |
| SCHEMBL24893418 | 0.87 | RAB9A (0.47) | ACACBPOLBALBJAK3ALDH1A1 | |
| SCHEMBL24893407 | 0.82 | MMP13 (0.46) | HTT | |
| SCHEMBL24893400 | 0.81 | SHMT2 (0.39) | ALBL3MBTL1SHMT2ALDH1A1 | |
| SCHEMBL24893374 | 0.79 | MEN1 (0.43) | ACACBPOLBALBJAK3SHMT2 | |
| SCHEMBL24893398 | 0.79 | TERT (0.46) | ACACBPOLBALBJAK3ALDH1A1 | |
| SCHEMBL24893376 | 0.77 | HTT (0.55) | POLBALDH1A1HTT | |
| SCHEMBL24893399 | 0.76 | NPC1 (0.43) | JAK3ALDH1A1HTT | |
| SCHEMBL24893377 | 0.76 | HTT (0.42) | JAK3ALDH1A1HTTPRKAA1 | |
| SCHEMBL24901393 | 0.76 | ADK (0.50) | FASNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285371-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2023-01-19 | — | — | WO | disclosed |
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |