SCHEMBL2489357

SCHEMBL2489357

C=COS(=O)(=O)CCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
NPC1 O15118 1/20 0.41
S1PR2 O95136 1/20 0.41
S1PR4 O95977 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
XBP1 P17861 1/20 0.41
S1PR1 P21453 1/20 0.41
MAPK1 P28482 1/20 0.41
AGTR1 P30556 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FAAH O00519 3/20 0.33
TSHR P16473 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4539381 0.93 FAAH (0.41) ALDH1A1HPGDNPC1S1PR2S1PR4
SCHEMBL29211208 0.91 FAAH (0.45) FAAHTSHRCA2CA1CA9
SCHEMBL2486748 0.86
SCHEMBL1628446 0.85
Acrylic Acid Methyl Ester SCHEMBL15637751 0.84 TSHR (0.43) ALDH1A1HPGDNPC1S1PR2S1PR4
SCHEMBL27853475 0.84
SCHEMBL3298086 0.83 ALDH1A1 (0.39) ALDH1A1HPGDNPC1S1PR2S1PR4
SCHEMBL27684502 0.79 NPC1 (0.43) ALDH1A1HPGDNPC1S1PR2S1PR4
SCHEMBL649701 0.78
SCHEMBL1713186 0.77 CA2 (0.31) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4267267-A HAVING A SUBBING LAYER OF A COPOLYMER OF VINYL CHLORIDE AND/OR VINYLIDENE CHLORIDE ON A GAS-PERBEABLE SUPPORT; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1981-05-12 US claimed
US-12612482-B2 Combination of crosslinkers to improve coating properties BASF SE (DE) 2026-04-28 US disclosed
US-20250361344-A1 STYRENE BUTADIENE LATEX BINDER FOR WATERPROOFING APPLICATIONS BASF SE (DE) 2025-11-27 US disclosed
US-20250243384-A1 DUAL CURABLE PRESSURE SENSITIVE ADHESIVE BASF SE (DE) 2025-07-31 US disclosed
US-20250092177-A1 BINDER COMPOSITIONS AND METHODS OF PREPARING AND USING THE SAME BASF SE (DE) 2025-03-20 US disclosed
EP-4504846-A1 DUAL CURABLE PRESSURE SENSITIVE ADHESIVE BASF SE (DE) 2025-02-12 EP disclosed
US-20240368391-A1 COATING COMPOSIONS WITH (STYRENE) ACRYLIC AND RUBBER BASF SE (DE) 2024-11-07 US disclosed
US-20240182745-A1 COATINGS WITH IMPROVED STAIN REMOVAL BASF SE (DE) 2024-06-06 US disclosed
US-20240150620-A1 MULTILAYER COMPOSITE WITH DUAL LAYER PRESSURE-SENSITIVE ADHESIVE BASF SE (DE) 2024-05-09 US disclosed
EP-4359483-A1 COATING COMPOSITIONS WITH (STYRENE) ACRYLIC AND RUBBER BASF SE (DE) 2024-05-01 EP disclosed
EP-0808855-A2 Fluorescent polymers and coating compositions ROHM AND HAAS COMPANY (US) 1997-11-26 EP disclosed
EP-0778297-A1 Hydrophilic copolymer, process for producing same, photosensitive composition, and photosensitive rubber plate NIPPON ZEON CO., LTD. (JP) 1997-06-11 EP disclosed
EP-0324568-B1 Water soluble polymers for detergent compositions ROHM & HAAS (US) 1994-09-07 EP disclosed
US-5143954-A LOW-FORMALDEHYDE, SELF-CROSSLINKING POLYMER LATEX COMPOSITION ROHM AND HAAS COMPANY (US) 1992-09-01 US disclosed
US-5130369-A Polymerization of a monomer with a chain transfer agent and a second monomer with the monomers interacting ROHM AND HAAS COMPANY (US) 1992-07-14 US disclosed
EP-0488605-A2 Low-formaldehyde self-crosslinking polymer latex composition ROHM AND HAAS COMPANY (US) 1992-06-03 EP disclosed
EP-0324569-A2 Process for preparing functionalized polymeric compositions ROHM AND HAAS COMPANY (US) 1989-07-19 EP disclosed
EP-0324568-A2 Water soluble polymers for detergent compositions ROHM AND HAAS COMPANY (US) 1989-07-19 EP disclosed
US-4797223-A ANIONIC, CATIONIC OR NONIONIC SURFACTANTS ROHM AND HAAS COMPANY (US) 1989-01-10 US disclosed
US-4267267-A HAVING A SUBBING LAYER OF A COPOLYMER OF VINYL CHLORIDE AND/OR VINYLIDENE CHLORIDE ON A GAS-PERBEABLE SUPPORT; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612482-B2 Combination of crosslinkers to improve coating properties BHMT2, FDFT1, MNAT1 ALDH1A1 619/4885HPGD 2783/4885NPC1 1740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.