SCHEMBL4539381

SCHEMBL4539381

C=COS(=O)(=O)CCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.41
CA2 P00918 13/20 0.38
NPC1 O15118 1/20 0.35
S1PR2 O95136 1/20 0.35
S1PR4 O95977 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
XBP1 P17861 1/20 0.35
S1PR1 P21453 1/20 0.35
MAPK1 P28482 1/20 0.35
AGTR1 P30556 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29211208 0.98 FAAH (0.45) FAAHCA2TSHRCA1CA9
SCHEMBL2489357 0.93 ALDH1A1 (0.41) FAAHCA2NPC1S1PR2S1PR4
SCHEMBL1628446 0.89
SCHEMBL2486748 0.84
SCHEMBL3319916 0.83 FAAH (0.39) FAAHCA2NPC1S1PR2S1PR4
SCHEMBL27853475 0.82
SCHEMBL3295254 0.82 FAAH (0.42) FAAHCA2TSHRCA1CA9
SCHEMBL6247258 0.80 FAAH (0.43) FAAHCA2NPC1S1PR2S1PR4
Acrylic Acid Methyl Ester SCHEMBL15637751 0.79 TSHR (0.43) CA2NPC1S1PR2S1PR4ALDH1A1
SCHEMBL27881702 0.78 FAAH (0.46) FAAHCA2TSHRCA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157152-A Compositions and methods for improving the efficacy of a drug 赫利昂生物股份有限公司 2023-05-23 CN claimed
WO-2009118753-A2 PROCESS FOR PREPARATION OF NARATRIPTAN HYDROCHLORIDE USV LIMITED (IN) 2009-10-01 WO claimed
EP-0311799-A1 Water dispersible hydrophobic thickening agent AMERICAN CYANAMID COMPANY (US) 1989-04-19 EP claimed
CN-116157152-A Compositions and methods for improving the efficacy of a drug 赫利昂生物股份有限公司 2023-05-23 CN disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
EP-3572202-B1 MOLDED ARTICLE AND METHOD FOR PRODUCING SAME SUMITOMO CHEMICAL CO (JP) 2021-08-11 EP disclosed
CN-107427414-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-07-02 CN disclosed
CN-112940432-A Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-06-11 CN disclosed
US-10941254-B2 Molded article and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-09 US disclosed
US-20190322815-A1 MOLDED ARTICLE AND METHOD OF PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-10-24 US disclosed
US-20190033503-A1 LIGHT-MODULATING MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-01-31 US disclosed
EP-2924228-B1 LIGHT-MODULATING MEMBER SUMITOMO CHEMICAL CO (JP) 2018-10-24 EP disclosed
US-20150309227-A1 LIGHT-MODULATING MEMBER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-29 US disclosed
EP-2924228-A1 LIGHT-MODULATING MEMBER Sumitomo Chemical Company Limited (JP) 2015-09-30 EP disclosed
CN-1809615-B Transparent resin composition SANYO CHEMICAL IND LTD 2010-05-05 CN disclosed
US-20090258966-A1 Dental Composition NIHON UNIVERSITY (JP) 2009-10-15 US disclosed
WO-2009118753-A2 PROCESS FOR PREPARATION OF NARATRIPTAN HYDROCHLORIDE USV LIMITED (IN) 2009-10-01 WO disclosed
CN-1809615-A Transparent resin composition SANYO CHEMICAL IND LTD (JP) 2006-07-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258966-A1 Dental Composition DCPS, MMAB, CAD FAAH 4656/4885CA2 149/4885NPC1 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.