SCHEMBL24901031

SCHEMBL24901031

O=C(Oc1ccc(F)c(F)c1F)C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.37
CES1 P23141 2/20 0.37
SCN8A Q9UQD0 1/20 0.32
SCN10A Q9Y5Y9 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
POLB P06746 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24901188 0.85 CES2 (0.39) CES2CES1
SCHEMBL10179556 0.84 CES2 (0.38) CES2CES1SCN8ASCN10AEPHX2
SCHEMBL10180776 0.84 CES2 (0.41) CES2CES1SCN8ASCN10ACYP4F2
SCHEMBL24901032 0.83 CES2 (0.31) CES2CES1
SCHEMBL24901181 0.78 TSHR (0.44) CES2CES1POLBNPSR1EPHX2
SCHEMBL24946068 0.77 FAAH (0.41) CES2CES1
SCHEMBL3827377 0.74 CES2 (0.45) CES2CES1SCN8ASCN10ACYP4F2
SCHEMBL17552759 0.73 RIPK1 (0.48) CES2CES1CYP4F2CYP4A11
SCHEMBL12636052 0.73 CES2 (0.41) CES2CES1CYP4F2CYP4A11
SCHEMBL24901099 0.72 CES2 (0.37) CES2CES1CYP4F2CYP4A11POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20230019681-A1 POSITIVE RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR CES2 1660/4885CES1 3887/4885SCN8A 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.