SCHEMBL24901074

SCHEMBL24901074

O=C(Oc1c(F)c(F)c(F)c(F)c1F)C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NR3C1 P04150 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401784 0.80 TSHR (0.33) TSHRSMN1; SMN2NR3C1
SCHEMBL40376 0.79 TSHR (0.35) TSHRSMN1; SMN2NR3C1
SCHEMBL13917867 0.77 NR3C1 (0.35) TSHRSMN1; SMN2NR3C1
SCHEMBL19105207 0.77 NR3C1 (0.35) TSHRSMN1; SMN2NR3C1
SCHEMBL24901029 0.76 CES2 (0.34)
SCHEMBL21389209 0.75 DGAT1 (0.34) TSHRSMN1; SMN2NR3C1
SCHEMBL12027013 0.75 ELANE (0.45) TSHRSMN1; SMN2NR3C1
SCHEMBL24901032 0.74 CES2 (0.31)
SCHEMBL17281562 0.72 NR3C1 (0.33) TSHRSMN1; SMN2NR3C1
SCHEMBL19105276 0.72 TSHR (0.35) TSHRSMN1; SMN2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20230019681-A1 POSITIVE RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR TSHR 2477/4885SMN1; SMN2 416/4885ALDH1A1 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.