SCHEMBL24901409

SCHEMBL24901409

O=C(OCc1c(F)c(F)cc(F)c1F)C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
MAOB P27338 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP12 P39900 1/20 0.31
POLB P06746 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.31
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24901419 0.90 MMP1 (0.33) CA1CA2CA4MAOBMMP1
SCHEMBL24142266 0.86 MMP1 (0.37) MMP1MMP2MMP9MMP12POLB
SCHEMBL23060386 0.82 CA1 (0.42) CA1CA2CA4MAOBMMP1
SCHEMBL24901410 0.81 MMP2 (0.33) MAOBMMP1MMP2MMP9MMP12
SCHEMBL24901418 0.80 MMP2 (0.43) MAOBMMP1MMP2MMP9MMP12
SCHEMBL26624237 0.76 CA1 (0.35) CA1CA2CA4MAOBCES2
SCHEMBL17552784 0.75 RIPK1 (0.43) MAOB
SCHEMBL24901134 0.75 MMP2 (0.42) CA1CA2MAOBMMP1MMP2
SCHEMBL24901131 0.74 MAOA (0.48) CA1CA2MAOBCES2CES1
SCHEMBL24901129 0.73 MMP1 (0.39) MAOBMMP1MMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-26 US disclosed
US-20230019681-A1 POSITIVE RESIST MATERIAL AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023593-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS HNRNPU, EWSR1, HNRNPR CA1 1590/4885CA2 849/4885CA4 1059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.