Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094227 | 0.78 | PIN1 (0.45) | MAPTPIN1EPHX2FBP1TSHR | |
| SCHEMBL22123345 | 0.77 | FBP1 (0.50) | PIN1FBP1CYP1A2ABCB11CYP3A4 | |
| SCHEMBL24901468 | 0.76 | KMT2A (0.43) | FBP1CYP1A2TSHRPOLBNPSR1 | |
| SCHEMBL24901718 | 0.76 | KCNA3 (0.34) | MAPTEPHX2FBP1CYP1A2ABCB11 | |
| SCHEMBL31697054 | 0.75 | PDE2A (0.34) | EPHX2 | |
| SCHEMBL22207999 | 0.75 | PDE2A (0.34) | EPHX2 | |
| SCHEMBL24901456 | 0.75 | — | — | |
| SCHEMBL24901695 | 0.74 | ALDH1A1 (0.49) | FBP1CYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL24901453 | 0.74 | ALDH1A1 (0.42) | MAPTCYP1A2TSHRPOLBLMNA | |
| SCHEMBL24901458 | 0.73 | FBP1 (0.46) | MAPTEPHX2FBP1CYP1A2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023286768-A1 | HYDROGENATED QUINOXALINES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | WO | disclosed |