Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29921177 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1PRKDCPTPN1PKM | |
| Tetrahydrofuran SCHEMBL28116418 | 0.86 | PTPN1 (0.36) | KDM4EALDH1A1PRKDCPTPN1PKM | |
| SCHEMBL42391 | 0.82 | ERN1 (0.42) | KDM4EALDH1A1PRKDCPTPN1PKM | |
| SCHEMBL21631066 | 0.79 | CDK4 (0.37) | ALDH1A1PKMLMNANFE2L2 | |
| SCHEMBL4363014 | 0.78 | ERN1 (0.46) | KDM4EALDH1A1PTPN1ERN1LMNA | |
| SCHEMBL29957006 | 0.78 | ERN1 (0.46) | KDM4EALDH1A1PTPN1ERN1LMNA | |
| SCHEMBL22097420 | 0.77 | NFE2L2 (0.36) | KDM4EPKMKMT2ANFE2L2BACE1 | |
| SCHEMBL27797116 | 0.77 | NFE2L2 (0.36) | KDM4EALDH1A1PKMLMNAMEN1 | |
| SCHEMBL12408701 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1PTPN1ERN1LMNA | |
| SCHEMBL18181691 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1PTPN1ERN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119116-A | Rhein phosphoryl derivative and synthetic method and application thereof | 甘肃中医药大学 | 2024-12-13 | — | — | CN | claimed |
| CN-118754902-A | Fluorescent probe based on rhodamine derivative substituted by silicon atoms, and preparation method and application thereof | 四川大学 | 2024-10-11 | — | — | CN | claimed |
| CN-108892616-B | Continuous device for preparing benzaldehyde intermediate and application thereof | 凯莱英生命科学技术(天津)有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117143091-A | HBV core protein degradation agent based on hydrophobic tag technology and preparation method and application thereof | 山东大学 | 2023-12-01 | — | — | CN | claimed |
| CN-113512035-B | Dihydropyrimidine-pomalidomide conjugate, and preparation method and application thereof | 山东大学 | 2023-11-24 | — | — | CN | claimed |
| CN-115536509-B | Synthesis method of 2-bromo-4-hydroxybenzaldehyde | 苏州当量生物医药有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116675687-A | Dihydropyrimidine derivative containing carboxylic acid and preparation method and application thereof | 山东大学 | 2023-09-01 | — | — | CN | claimed |
| CN-108997310-B | Asymmetric 3-pyridine substituted 3, 5-diarylmethylene-4-piperidone and preparation method thereof | 滨州医学院 | 2023-06-27 | — | — | CN | claimed |
| CN-108997311-B | Asymmetric 4-pyridine substituted 3, 5-diarylmethylene-4-piperidone and preparation method thereof | 滨州医学院 | 2023-06-23 | — | — | CN | claimed |
| CN-116284080-A | Dihydropyrimidine derivative containing boric acid and boric acid pinacol ester group, and preparation method and application thereof | 山东大学 | 2023-06-23 | — | — | CN | claimed |
| US-10017684-B2 | Method and compositions for hydraulic fracturing and for tracing formation water | SPECTRUM TRACER SERVICES, LLC (US) | 2018-07-10 | — | — | US | claimed |
| CN-108191769-A | A kind of preparation method of olaparib | 山东裕欣药业有限公司 | 2018-06-22 | — | — | CN | claimed |
| CN-107501257-A | Dihydro-pyrimidin triazole derivative and preparation method and application | 山东大学 | 2017-12-22 | — | — | CN | claimed |
| US-20170306217-A1 | METHOD AND COMPOSITIONS FOR HYDRAULIC FRACTURING AND FOR TRACING FORMATION WATER | NCS Multistage, LLC | 2017-10-26 | — | — | US | claimed |
| CN-107188851-A | A kind of method for synthesizing astemizole key intermediate and its derivative | 湖南大学 | 2017-09-22 | — | — | CN | claimed |
| CN-107011379-A | Phosphine epoxide red orange photo-thermal excites delayed fluorescence material, synthetic method and its application | 黑龙江大学 | 2017-08-04 | — | — | CN | claimed |
| CN-105646337-A | Tert-butyl substituted asymmetrical piperidone compounds with anti-tumor activities and preparation method thereof | 滨州医学院 | 2016-06-08 | — | — | CN | claimed |
| CN-102532640-B | Method of nucleating polyolefin composition with acetal-based compound | MILLIKEN & CO | 2014-11-26 | — | — | CN | claimed |
| CN-103429594-A | Process for preparation of acetals | RELIANCE IND LTD | 2013-12-04 | — | — | CN | claimed |
| CN-103415523-A | Process for preparing alditol acetals | RELIANCE IND LTD | 2013-11-27 | — | — | CN | claimed |