Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29921177 | 0.86 | KDM4E (0.42) | PTPN1PRKDCKMT2AKDM4EALDH1A1 | |
| SCHEMBL249018 | 0.86 | KDM4E (0.42) | PTPN1PRKDCKMT2AKDM4EALDH1A1 | |
| Tetrahydrofuran SCHEMBL28119237 | 0.77 | CA3 (0.35) | KMT2AKDM4EALDH1A1MEN1GRIN2B | |
| SCHEMBL29257280 | 0.75 | RAB9A (0.36) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL42391 | 0.70 | ERN1 (0.42) | PTPN1PRKDCKDM4EALDH1A1PKM | |
| SCHEMBL6225982 | 0.69 | PRKDC (0.51) | NPC1RAB9ASMN1; SMN2PRKDCPIK3CA | |
| SCHEMBL21631066 | 0.68 | CDK4 (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL4363014 | 0.67 | ERN1 (0.46) | PTPN1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL29957006 | 0.67 | ERN1 (0.46) | PTPN1KMT2AKDM4EALDH1A1MEN1 | |
| Tetrahydrofuran SCHEMBL127554 | 0.66 | LMNA (0.39) | SMN1; SMN2KMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279082-A | Substituted furan chalcone derivant and preparation method thereof | 浙江大学 | 2017-01-04 | — | — | CN | disclosed |