Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 5/20 | 0.40 |
| ▸ | COMT | P21964 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919619 | 0.80 | ITGA4 (0.49) | ITGB1ITGA4ITGB7 | |
| SCHEMBL11903442 | 0.75 | MAPT (0.44) | ITGB1ITGA4ITGB7KCNH2MAPT | |
| SCHEMBL512819 | 0.73 | ITGB1 (0.39) | ITGB1ITGA4ITGB7KCNH2COMT | |
| SCHEMBL12160455 | 0.70 | KAT2B (0.56) | MAPTRAB9A | |
| SCHEMBL510385 | 0.69 | ACLY (0.35) | ITGB1ITGA4ITGB7MAPT | |
| SCHEMBL31104098 | 0.68 | KAT2B (0.39) | COMTMAPTRAB9A | |
| SCHEMBL14352940 | 0.68 | AR (0.52) | KMT2AHTTMEN1COMTPOLB | |
| SCHEMBL11910054 | 0.67 | F7 (0.44) | ITGB1ITGA4ITGB7MAPTRAB9A | |
| SCHEMBL2642058 | 0.67 | KAT2B (0.47) | HTTNPC1MAPT | |
| SCHEMBL23087540 | 0.66 | AKT1 (0.49) | KCNH2PRMT5WDR77AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| EP-2379509-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | Bayer CropScience AG (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| WO-2010078912-A1 | PHENYL-SUBSTITUTED PYRIDAZINONE ACTING AS HERBICIDE AND INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2010-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | ITGB1 2829/4885ITGA4 3401/4885ITGB7 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.