Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.38 |
| ▸ | ACACA | Q13085 | 5/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903442 | 0.78 | MAPT (0.44) | ITGB1ITGA4ITGB7KCNH2 | |
| SCHEMBL11910054 | 0.76 | F7 (0.44) | ITGB1ITGA4ITGB7BRD4PTGS2 | |
| SCHEMBL2490210 | 0.73 | ITGB1 (0.47) | ITGB1ITGA4ITGB7KCNH2COMT | |
| SCHEMBL3064869 | 0.71 | NPC1 (0.41) | ITGB1ITGA4ITGB7BRD4PTGS2 | |
| SCHEMBL5536077 | 0.70 | ACACB (0.42) | ACACBACACAALOX5HTR2CJAK2 | |
| SCHEMBL510385 | 0.69 | ACLY (0.35) | ITGB1ITGA4ITGB7BRD4 | |
| SCHEMBL15282244 | 0.68 | NPC1 (0.40) | PTGS2 | |
| SCHEMBL470078 | 0.68 | NPC1 (0.36) | BRD4MAP2K1KCNH2GRIN2B | |
| SCHEMBL512528 | 0.68 | LMNA (0.37) | BRD4 | |
| SCHEMBL919079 | 0.67 | BRD9 (0.34) | ITGB1ITGA4ITGB7BRD4PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028988-A1 | USE OF PYRIDAZINONE COMPOUND FOR CONTROL OF HARMFUL ARTHROPOD PESTS | PLPBP, PNPO, PIR | ITGB1 1030/4885ITGA4 1752/4885ITGB7 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.