Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 18/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490210 | 0.80 | ITGB1 (0.47) | ITGA4ITGB7ITGB1 | |
| SCHEMBL8280366 | 0.80 | ITGA4 (0.54) | ITGA4ITGB7ITGB1 | |
| SCHEMBL466352 | 0.72 | ALDH1A1 (0.55) | — | |
| SCHEMBL513273 | 0.71 | ALDH1A1 (0.40) | ITGA4ITGB7ITGB1 | |
| SCHEMBL509614 | 0.71 | CRHR1 (0.41) | ITGA4ITGB7ITGB1 | |
| SCHEMBL4512412 | 0.68 | ITGA4 (0.70) | ITGA4ITGB7ITGB1 | |
| SCHEMBL4512416 | 0.68 | ITGA4 (0.70) | ITGA4ITGB7ITGB1 | |
| SCHEMBL10508607 | 0.67 | NPSR1 (0.67) | — | |
| SCHEMBL466422 | 0.67 | ITGA4 (0.42) | ITGA4ITGB7ITGB1 | |
| SCHEMBL14844549 | 0.67 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242055-B2 | Herbicidally and insecticidally active phenyl-substituted pyridazinones | BAYER CROPSCIENCE AG (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20110003692-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2204366-A1 | Herbicidal and insecticidal phenyl-substituted pyridazinones | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2010069526-A1 | HERBICIDALLY AND INSECTICIDALLY EFFECTIVE PHENYL-SUBSTITUED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184602-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | ITGA4 3401/4885ITGB7 2899/4885ITGB1 2829/4885 |
| US-20110003692-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | CYP4X1, PRDX1, PNPO | ITGA4 3401/4885ITGB7 2899/4885ITGB1 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.