Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23417226 | 0.86 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL25068449 | 0.79 | CA12 (0.48) | ALDH1A1MAPK1KMT2AKDM4E | |
| SCHEMBL23417228 | 0.77 | ALDH1A1 (0.46) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL23693471 | 0.74 | PTGS2 (0.38) | — | |
| SCHEMBL10192089 | 0.72 | TSHR (0.70) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL25848742 | 0.71 | TSHR (0.65) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL18862468 | 0.71 | TSHR (0.68) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL28752749 | 0.69 | TSHR (0.64) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3954491 | 0.67 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3954482 | 0.66 | TSHR (0.46) | TSHRL3MBTL1ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | Infex Therapeutics Limited (GB) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230018460-A1 | 1-AMINOSULFONYL-2-CARBOXYPYRROLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | CPN1, CMBL, ALDH7A1 | TSHR 4739/4885L3MBTL1 1631/4885ALDH1A1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.