Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | BRD1 | O95696 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192089 | 0.84 | TSHR (0.70) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL18862468 | 0.82 | TSHR (0.68) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL28752749 | 0.79 | TSHR (0.64) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL23113013 | 0.74 | TSHR (0.57) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7921928 | 0.73 | LMNA (0.51) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL24904403 | 0.71 | TSHR (0.51) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4070446 | 0.71 | LMNA (0.55) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL5396577 | 0.70 | GLO1 (0.44) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL289059 | 0.70 | LMNA (0.54) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL420412 | 0.70 | LMNA (0.54) | TSHRL3MBTL1ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793990-B1 | ANTIBACTERIAL COMPOUNDS | INFEX THERAPEUTICS LTD (GB) | 2023-07-19 | — | — | EP | disclosed |