Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 6/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564471 | 0.84 | PTPN1 (0.61) | DUSP3PTPN1TP53 | |
| SCHEMBL1686409 | 0.83 | ALOX5AP (0.50) | DUSP3PTPN1TRPV1RXRANR4A2 | |
| SCHEMBL1686323 | 0.83 | KMO (0.45) | DUSP3PTPN1NPC1RAB9ARXRA | |
| SCHEMBL4337496 | 0.82 | DUSP3 (0.56) | DUSP3PTPN1PIN1TRPV1NPC1 | |
| SCHEMBL11373825 | 0.79 | FABP3 (0.48) | DUSP3PTPN1PIN1TRPV1NPC1 | |
| SCHEMBL1227041 | 0.76 | DUSP3 (0.56) | DUSP3PTPN1PIN1TRPV1NPC1 | |
| SCHEMBL1686554 | 0.75 | PTPN1 (0.45) | DUSP3PTPN1TRPV1MAPT | |
| SCHEMBL1686474 | 0.75 | PTPN1 (0.45) | DUSP3PTPN1TRPV1NPC1RAB9A | |
| SCHEMBL1545025 | 0.74 | L3MBTL1 (0.53) | TRPV1L3MBTL1MAPTTP53PDE4B | |
| SCHEMBL1226204 | 0.73 | PTPN1 (0.58) | DUSP3PTPN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313172-A1 | PROCESS FOR THE PREPARATION OF 1-[5-(3-CHLORO-PHENYL)-ISOOXAZOL-3-YL]-ETHANONE AND (R)-1-[5-(3-CHLORO-PHENYL)-ISOOXAZOL-3-YL]-ETHANOL | ASTRAZENECA AB (SE) | 2011-12-22 | — | — | US | disclosed |
| EP-2379514-A1 | NEW PROCESS FOR THE PREPARATION OF 1- [5- (3-CHLORO-PHENYL) - ISOOXAZOL-3-YL]-ETHANONE AND (R) -1- [5- (3-CHLORO-PHENYL) - ISOOXAZOL-3-YL]-ETHANOL | AstraZeneca AB (SE) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010071558-A1 | NEW PROCESS FOR THE PREPARATION OF 1- [5- (3-CHLORO-PHENYL) - ISOOXAZOL-3-YL] -ETHANONE AND (R) -1- [5- (3-CHLORO-PHENYL) - ISOOXAZOL-3-YL] -ETHANOL | ASTRAZENECA AB (SE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313172-A1 | PROCESS FOR THE PREPARATION OF 1-[5-(3-CHLORO-PHENYL)-ISOOXAZOL-3-YL]-ETHANONE AND (R)-1-[5-(3-CHLORO-PHENYL)-ISOOXAZOL-3-YL]-ETHANOL | ADH1C, ADH1A, GK | DUSP3 3998/4885PTPN1 3948/4885PIN1 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.