Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340875 | 1.00 | NAMPT (0.45) | NAMPTCNR1CNR2CASP2FAAH | |
| SCHEMBL24193602 | 0.95 | CNR1 (0.43) | NAMPTCNR1CNR2CASP2FAAH | |
| SCHEMBL24490138 | 0.90 | LMNA (0.50) | NAMPTCNR1CNR2FAAHLMNA | |
| SCHEMBL23788658 | 0.90 | CNR1 (0.44) | NAMPTCNR1CNR2FAAHLMNA | |
| SCHEMBL24950257 | 0.89 | LMNA (0.51) | NAMPTCNR1CNR2FAAHLMNA | |
| SCHEMBL22664216 | 0.88 | CASP2 (0.52) | CASP2FAAHNAAAMEN1TSHR | |
| SCHEMBL22664245 | 0.88 | CASP2 (0.52) | CASP2FAAHNAAAMEN1TSHR | |
| SCHEMBL10633582 | 0.88 | CASP2 (0.52) | CASP2FAAHNAAAMEN1TSHR | |
| SCHEMBL10345306 | 0.88 | NAMPT (0.52) | NAMPTCNR1CNR2CASP2FAAH | |
| SCHEMBL24818366 | 0.88 | NAMPT (0.52) | NAMPTCNR1CNR2CASP2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022590-A1 | NOVEL RNA THERAPEUTICS AND USES THEREOF | ELI LILLY AND COMPANY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022590-A1 | NOVEL RNA THERAPEUTICS AND USES THEREOF | RNASE1, TEK, HDGFL3 | NAMPT 1007/4885CNR1 4380/4885CNR2 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.