SCHEMBL24909398

SCHEMBL24909398

Cc1sncc1-c1cc(C#N)cc(C(F)(F)F)c1O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.33
ALB P02768 1/20 0.33
LRRK2 Q5S007 1/20 0.31
KDM4E B2RXH2 1/20 0.31
XDH P47989 2/20 0.31
SLC22A12 Q96S37 2/20 0.31
TRPV4 Q9HBA0 1/20 0.31
CYP2C9 P11712 1/20 0.31
AR P10275 1/20 0.30
P4HB P07237 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909782 0.77 TRPV4 (0.34) TTRALBXDHSLC22A12TRPV4
SCHEMBL24909734 0.76 AURKA (0.39) TTRALBXDHSLC22A12TRPV4
SCHEMBL24909786 0.75 GYS1 (0.33) TTRALBLRRK2XDHSLC22A12
SCHEMBL24909781 0.75 PDE3B (0.37) TTRALBXDHSLC22A12TRPV4
SCHEMBL24909944 0.73 PDK2 (0.37) TTRALBLRRK2KDM4EXDH
SCHEMBL24909738 0.73 CYP11B2 (0.56) TTRALBLRRK2KDM4EXDH
SCHEMBL24909900 0.73 LRRK2 (0.35) TTRALBLRRK2KDM4EXDH
SCHEMBL24909752 0.72 ELANE (0.35) TTRALBLRRK2XDHSLC22A12
SCHEMBL24909746 0.71 GYS1 (0.35) TTRALBLRRK2XDHSLC22A12
SCHEMBL24909915 0.70 KIF11 (0.41) TTRALBXDHSLC22A12TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 TTR 4497/4885ALB 3928/4885LRRK2 2146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.