SCHEMBL24909752

SCHEMBL24909752

N#Cc1cc(-c2cncs2)c(O)c(C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.35
ACLY P53396 1/20 0.35
MYC P01106 1/20 0.35
XDH P47989 3/20 0.33
SLC22A12 Q96S37 3/20 0.33
TTR P02766 2/20 0.33
ALB P02768 2/20 0.33
KIF11 P52732 1/20 0.33
CYP19A1 P11511 1/20 0.32
AR P10275 3/20 0.32
PGR P06401 1/20 0.32
GYS1 P13807 1/20 0.32
TRPV4 Q9HBA0 1/20 0.31
LRRK2 Q5S007 1/20 0.31
P4HB P07237 1/20 0.30
ABL1 P00519 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909806 0.79 TRPV4 (0.33) XDHSLC22A12TTRALBKIF11
SCHEMBL24909734 0.77 AURKA (0.39) XDHSLC22A12TTRALBKIF11
SCHEMBL24909947 0.75 HSD17B1 (0.37) XDHSLC22A12KIF11CYP19A1AR
SCHEMBL24909786 0.74 GYS1 (0.33) XDHSLC22A12TTRALBAR
SCHEMBL24910069 0.74 DAO (0.34) XDHSLC22A12TRPV4
SCHEMBL24909792 0.73 CYP11B2 (0.45) XDHSLC22A12KIF11ARPGR
SCHEMBL24909804 0.73 IDH1 (0.40) XDHSLC22A12TTRALBKIF11
SCHEMBL31097123 0.73 CRHR1 (0.41) XDHSLC22A12CYP19A1ARGYS1
SCHEMBL24909781 0.73 PDE3B (0.37) XDHSLC22A12TTRALBKIF11
SCHEMBL24909746 0.72 GYS1 (0.35) XDHSLC22A12TTRALBKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 ELANE 3958/4885ACLY 204/4885MYC 4447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.