Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24909891 | 0.95 | AR (0.43) | ARPGRAKR1C3AKR1C2GRM5 | |
| SCHEMBL24909915 | 0.86 | KIF11 (0.41) | ARPGRVEGFAKIF11 | |
| SCHEMBL24909774 | 0.85 | KIF11 (0.40) | ARPGRGRM5VEGFAKIF11 | |
| SCHEMBL24909923 | 0.83 | KIF11 (0.36) | ARPGRSSTR2KIF11 | |
| SCHEMBL24909890 | 0.82 | CYP11B1 (0.47) | ARPGRKDM4EMAPTLRRK2 | |
| SCHEMBL24910000 | 0.82 | TTR (0.47) | PGRAKR1C3AKR1C2GRM5VEGFA | |
| SCHEMBL24909727 | 0.80 | KIF11 (0.36) | ARPGRGRM5SSTR2KDM4E | |
| SCHEMBL24909934 | 0.78 | KIF11 (0.45) | ARPGRKIF11 | |
| SCHEMBL24910014 | 0.77 | KIF11 (0.38) | ARPGRKIF11 | |
| SCHEMBL24909762 | 0.75 | RXRA (0.46) | ARPGRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024283-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024283-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | AR 3997/4885PGR 4667/4885AKR1C3 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.