SCHEMBL24909762

SCHEMBL24909762

N#Cc1cc(-c2cc(C#N)cc(C(F)(F)F)c2O)cc(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.46
RXRG P48443 1/20 0.46
XDH P47989 3/20 0.41
KIF11 P52732 2/20 0.38
TMPRSS4 Q9NRS4 1/20 0.36
SLC22A12 Q96S37 2/20 0.36
TAS2R14 Q9NYV8 1/20 0.35
CYP1A2 P05177 1/20 0.35
METAP2 P50579 1/20 0.35
AR P10275 5/20 0.35
PGR P06401 1/20 0.35
TRPV4 Q9HBA0 1/20 0.34
TTR P02766 2/20 0.33
ALB P02768 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
P4HB P07237 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24909774 0.86 KIF11 (0.40) XDHKIF11SLC22A12ARPGR
SCHEMBL24909915 0.84 KIF11 (0.41) XDHKIF11SLC22A12ARPGR
SCHEMBL24909724 0.84 TTR (0.51) RXRARXRGXDHKIF11TMPRSS4
SCHEMBL24909792 0.83 CYP11B2 (0.45) RXRARXRGXDHKIF11SLC22A12
SCHEMBL24909934 0.82 KIF11 (0.45) XDHKIF11SLC22A12ARPGR
SCHEMBL24910014 0.81 KIF11 (0.38) XDHKIF11SLC22A12ARPGR
SCHEMBL24910055 0.81 PDK2 (0.44) XDHKIF11SLC22A12ARPGR
SCHEMBL24909891 0.79 AR (0.43) XDHSLC22A12ARPGRTTR
SCHEMBL24910040 0.79 TRPV4 (0.35) XDHKIF11SLC22A12ARPGR
SCHEMBL24909727 0.78 KIF11 (0.36) XDHKIF11SLC22A12CYP1A2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024283-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230024283-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 RXRA 2680/4885RXRG 2415/4885XDH 662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.