SCHEMBL2490977

SCHEMBL2490977

C=Cc1cc(F)c(F)c(F)c1C=C

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27925103 0.85
SCHEMBL21382509 0.82 CA1 (0.36) CA12CA1CA2CA7CA13
SCHEMBL31448050 0.81 ESR1 (0.31)
SCHEMBL970210 0.81 ESR1 (0.31)
SCHEMBL2485696 0.78
SCHEMBL10342220 0.78
SCHEMBL23269444 0.78 P2RX7 (0.32)
SCHEMBL13419496 0.76 CA12 (0.32) CA12CA1CA2CA7CA13
SCHEMBL13419498 0.76
SCHEMBL941259 0.76 CA1 (0.39) CA12CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10507174-B2 Skin care compositions ROHM AND HAAS COMPANY (US) 2019-12-17 US claimed
CN-107949367-B Skin care compositions 罗门哈斯公司 2021-07-09 CN disclosed
US-20200337951-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND INORGANIC METAL OXIDES ROHM & HAAS (US) 2020-10-29 US disclosed
EP-3355852-B1 SUNSCREEN COMPOSITIONS ROHM & HAAS (US) 2020-04-08 EP disclosed
US-10507174-B2 Skin care compositions ROHM AND HAAS COMPANY (US) 2019-12-17 US disclosed
WO-2019182714-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND IR ACTIVES DOW GLOBAL TECHNOLOGIES LLC (US) 2019-09-26 WO disclosed
US-20180280280-A1 SKIN CARE COMPOSITIONS ROHM AND HAAS COMPANY 2018-10-04 US disclosed
US-20180221254-A1 COMPOSITIONS CONTAINING LATEX PARTICLES AND INORGANIC METAL OXIDES ROHM AND HAAS COMPANY (US) 2018-08-09 US disclosed
EP-3355852-A1 SKIN CARE COMPOSITIONS Rohm and Haas Company (US) 2018-08-08 EP disclosed
EP-3331489-A1 COMPOSITIONS CONTAINING VOIDED LATEX PARTICLES AND INORGANIC METAL OXIDES Rohm and Haas Company (US) 2018-06-13 EP disclosed
EP-1632281-A1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM AND HAAS COMPANY (US) 2006-03-08 EP disclosed
US-20050203215-A1 Polymer carriers and process UGAZIO STEPHEN P J (FR) 2005-09-15 US disclosed
EP-1574534-A1 Polymer carriers and process ROHM AND HAAS COMPANY (US) 2005-09-14 EP disclosed
US-20050131143-A1 Oil absorbing composition and process ROHM AND HAAS FRANCE, S.A.S. (FR) 2005-06-16 US disclosed
EP-1514658-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-16 EP disclosed
EP-1510318-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-02 EP disclosed
US-20050043458-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY 2005-02-24 US disclosed
US-20050043453-A1 Process for manufacturing polymers CHANG CHING-JEN (US) 2005-02-24 US disclosed
US-6384104-B1 PROVIDING STORAGE STABILITY TO ULTRAVIOLET RADIATION ABSORPTION COMPOSITIONS BY ADDING LATEX POLYMER PARTICLES TO INCREASE ABSORPTION, WHEREIN PARTICLES CONTAIN VOID, HAVE SPECIFIED PARTICLE SIZE AND COMPRISE CROSSLINKED SHELL PORTION ROHM AND HAAS COMPANY 2002-05-07 US disclosed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180280280-A1 SKIN CARE COMPOSITIONS CUTA, MMS19, SOD1 CA12 3732/4885CA1 3944/4885CA2 3520/4885
US-10507174-B2 Skin care compositions CUTA, MMS19, SOD1 CA12 3732/4885CA1 3944/4885CA2 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.